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gpt-5-1-thinking[edit | edit source]

User: How many cases of rabies in the U.S.[edit | edit source]

How many cases of rabies in the U.S. a year?

Assistant: For humans in the U.S.:[edit | edit source]

For humans in the U.S.:

  • Human rabies cases: typically 1–3 cases per year are reported nationwide. NFID[2]
  • In recent decades it has never exceeded 10 per year, and many years have zero deaths. CDC[3]

For context (not what you asked, but related):

  • Animal rabies cases: about 4,000 confirmed rabid animals per year, mostly wildlife (bats, raccoons, skunks, foxes). AAHA[4]
  • Roughly 60,000–100,000 people a year in the U.S. get post-exposure prophylaxis (PEP) after potential exposure. CDC[5]

User: How many cases since 1978[edit | edit source]

How many cases since 1978

Assistant: Short answer: we don’t have an exact published total for “since 1978,” but we can bracket it pretty tightly.[edit | edit source]

Short answer: we don’t have an exact published total for “since 1978,” but we can bracket it pretty tightly.

What we do know:

  • CDC analysis: 125 human rabies cases in the U.S. from 1960–2018. CDC[6]
  • Classic review: 38 cases from 1960–1979. PubMed[7]
  • So 1980–2018 = 125 − 38 ≈ 87 cases.
  • Recent CDC / surveillance data: - 2019: 0 - 2020: 0 - 2021: 5 deaths Wikipedia[8] - 2022: 0 Wikipedia[9] - 2023: 0 (no human cases in North America) PubMed[10] - 2024: 3 deaths (California, Minnesota, Kentucky) Wikipedia[11] - 2025 so far: 1 transplant-related death People.com[12]

That gives 9 cases from 2019–2025, so 1980–2025 ≈ 87 + 9 = 96 cases.

For 1978–79, we know of at least 4 bat-variant human cases (2 in 1978, 2 in 1979) from CDC/Texas tables, but there were likely a few additional non-bat cases; the detailed year-by-year breakdown for those two years isn’t accessible in a single open table. Texas Health Services[13]

Putting it together:

  • Best estimate for U.S. human rabies cases from 1978 through early 2025: ≈100 cases total (roughly 96–105, depending on the exact 1978–79 count).

So: order of magnitude is about one hundred human cases in nearly 50 years, with only 0–5 per year and many years with none.

References[edit | edit source]

  1. ↑ "Rabies cases in U.S." ChatGPT. Retrieved 2025-12-07.
  2. ↑ "NFID". nfid.org. Retrieved 2025-12-07.
  3. ↑ "CDC". cdc.gov. Retrieved 2025-12-07.
  4. ↑ "AAHA". aaha.org. Retrieved 2025-12-07.
  5. ↑ "CDC". cdc.gov. Retrieved 2025-12-07.
  6. ↑ "CDC". cdc.gov. Retrieved 2025-12-07.
  7. ↑ "PubMed". pubmed.ncbi.nlm.nih.gov. Retrieved 2025-12-07.
  8. ↑ "Wikipedia". en.wikipedia.org. Retrieved 2025-12-07.
  9. ↑ "Wikipedia". en.wikipedia.org. Retrieved 2025-12-07.
  10. ↑ "PubMed". pubmed.ncbi.nlm.nih.gov. Retrieved 2025-12-07.
  11. ↑ "Wikipedia". en.wikipedia.org. Retrieved 2025-12-07.
  12. ↑ "People.com". people.com. Retrieved 2025-12-07.
  13. ↑ "Texas Health Services" (PDF). Texas Health Services. Retrieved 2025-12-07.
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