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Assistant: 來源資訊[edit | edit source]

來源資訊[edit | edit source]

  • 來源:JAMA(JAMA Network)
  • 日期:2025-12-16(Volume 334, Number 23)
  • 主題:New issue: Update to SOFA Score in Critically Ill Patients (SOFA-2), AI vs Human Coaching for Diabetes Prevention, Cutaneous Melanoma Review

本期快選(最多 5 篇)[edit | edit source]

  • Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score[2]-2%20Score)|類型:Original study|一句導讀:330 萬 ICU 建模驗證,AUROC 0.79 優於 SOFA 0.77,重症分層可更新。 JAMA Network[3]
  • An AI-Powered Lifestyle Intervention vs Human Coaching in the Diabetes Prevention Program: A Randomized Clinical Trial[4]|類型:Original study|一句導讀:724 人 RCT,AI 介入複合達標不劣於人類教練(差 1.0%,95%CI −6.1~8.1)。 JAMA Network[5]
  • Arsenic Exposure Reduction and Chronic Disease Mortality[6]|類型:Original study|一句導讀:尿砷每 IQR 下降 197 μg/g,慢性病死亡 aHR 0.78;高→低於中位數 aHR 0.46。 PubMed[7]
  • Cutaneous Melanoma: A Review[8]|類型:Review|一句導讀:黑色素瘤 95% 為皮膚型;全球年約 30 萬新案,早期手術、進展期免疫/標靶重點整理。 JAMA Network[9]
  • Recurrent Clostridioides difficile Infections[10]|類型:JAMA Insights|一句導讀:復發 CDI 的診斷、治療與再發預防流程化整理,臨床可直接套用。 JAMA Network[11]

全部條目導讀(依輸入出現順序)[edit | edit source]

This Week in JAMA[edit | edit source]

  • Audio Highlights: November 21, 2025[12] 中文標題:音訊精華(2025/11/21) 類型:Audio(This Week in JAMA) 導讀:用短音訊快速掃描本期重點(含肺癌篩檢、周邊神經病變回顧、砷暴露與死亡等),適合作為「先聽再挑文」的入口。 JAMA Network[13]

Original Investigation[edit | edit source]

  • An AI-Powered Lifestyle Intervention vs Human Coaching in the Diabetes Prevention Program: A Randomized Clinical Trial[14] 中文標題:糖尿病預防計畫:AI 生活型態介入 vs 人類教練的隨機試驗 類型:Original study(RCT;AI in Medicine) 導讀:RCT(n=724,前期糖尿病):AI vs 人類教練。12 月複合達標 42.4% vs 41.4%,差 1.0%(95%CI −6.1~8.1)達非劣;活動量未非劣。 JAMA Network[15]
  • Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score[16]-2%20Score) 中文標題:SOFA-2 器官衰竭評分的開發與驗證 類型:Original study(預後/風險評分開發與驗證;Caring for the Critically Ill Patient) 導讀:330 萬成人 ICU 聯邦分析建模驗證;SOFA-2(0–24,納用藥/器官支持)院內死亡 AUROC 0.79 優於 SOFA 0.77,利於重症分層更新;GI/免疫未納入。 JAMA Network[17]
  • Arsenic Exposure Reduction and Chronic Disease Mortality[18] 中文標題:砷暴露下降與慢性病死亡率 類型:Original study(前瞻性隊列;環境健康) 導讀:前瞻隊列(10,977 人)追蹤至 2022:尿砷每 IQR↓197 μg/g,慢性病死亡 aHR 0.78;高→低於中位數 aHR 0.46,支持砷緩解與死亡下降相關。 PubMed[19]

Research Letter[edit | edit source]

  • Tracking County-Level Measles Cases in the US[20] 中文標題:美國郡級麻疹病例追蹤平台 類型:Research Letter(病例序列/監測資料) 導讀:介紹可追蹤美國「郡級」麻疹病例的公共資料平台與更新方式,對公衛監測、疫情溝通與資源配置有直接用途。 JAMA Network[21]
  • Emergency Medicaid Spending for Undocumented Immigrants in the US[22] 中文標題:美國無證移民的 Emergency Medicaid 支出概況 類型:Research Letter(橫斷面/行政資料分析) 導讀:19 州 Medicaid claims 分析:Emergency Medicaid 佔總支出 2%(0.8%–4.1%),且 85% 支出用於美國出生/合法居留者;可校正政策討論的基線認知。 JAMA Network[23]

Viewpoint[edit | edit source]

  • Advisory Committee on Immunization Practices Standards for Assessing Evidence[24] 中文標題:ACIP 評估疫苗證據的標準 類型:Viewpoint 導讀:聚焦 ACIP 如何(以及應如何)評讀與分級證據,幫助臨床/公衛讀者理解建議形成、透明度與不確定性溝通的關鍵。 JAMA Network[25]
  • State Mifepristone Regulation Following GenBioPro v Raynes[26] 中文標題:GenBioPro v Raynes 後州層級米非司酮管制的變化 類型:Viewpoint(Women's Health;政策/法規) 導讀:梳理判決後各州對 mifepristone 的管制差異與趨勢,適合關注生殖健康服務可近性、醫療機構合規與臨床流程者。 JAMA Network[27]
  • Evolving Hospital-at-Home to Meet the Needs of Children[28] 中文標題:兒科 Hospital-at-Home 的模式演進 類型:Viewpoint(醫療交付模式) 導讀:討論兒科居家住院如何從成人模式調整(安全、照護負擔、支付與公平),可作為建置/擴張兒科 HaH 專案的框架文章。 JAMA Network[29]
  • The Make America Healthy Again Strategy Report[30] 中文標題:「Make America Healthy Again」策略報告的公共衛生觀點 類型:Viewpoint(健康政策) 導讀:從公共衛生與政策角度討論該策略報告的重點與可能影響,適合關注健康政策、風險溝通與健康不平等議題的讀者。 JAMA Network[31]

A Piece of My Mind[edit | edit source]

  • The Last Night[32] 中文標題:最後一夜(醫療人文敘事) 類型:A Piece of My Mind(敘事散文) 導讀:以臨床照護情境書寫「最後一夜」的情感與專業界線;若想從人文視角補足純研究文章讀感,這篇值得快讀。 JAMA Network[33]

Editorial[edit | edit source]

  • Artificial Intelligence and Diabetes Prevention[34] 中文標題:AI 與糖尿病預防:社論解讀 類型:Editorial(AI in Medicine) 導讀:搭配 AI vs 人類教練 DPP 試驗閱讀,社論聚焦 AI 介入的可近性、品質控管與監測重點,幫助判斷是否適合大規模部署。 JAMA Network[35]
  • A Revision to Organ Failure Assessment in Critically Ill Patients[36] 中文標題:重症器官衰竭評估的修訂:社論 類型:Editorial(重症照護) 導讀:解讀 SOFA-2 的核心改動與臨床意涵(納入治療/器官支持、預測力提升),並提醒使用情境與未涵蓋器官系統等限制。 JAMA Network[37]

Review[edit | edit source]

  • Cutaneous Melanoma: A Review[38] 中文標題:皮膚黑色素瘤:回顧 類型:Review(皮膚科/腫瘤;可做測驗) 導讀:皮膚型占約 95%;全球每年約 30 萬新案、9.6 萬死。早期以手術切除為主,進展期以免疫檢查點抑制與標靶治療;強調早期辨識與多專科照護。 JAMA Network[39]

JAMA Guide to Statistics and Methods[edit | edit source]

  • Pattern-Mixture Models for Missing Data[40] 中文標題:缺失資料的 Pattern-Mixture Models 類型:Methods/Statistics(JAMA Guide to Statistics and Methods) 導讀:當缺失資料可能非隨機(MNAR)時,pattern-mixture models 以「缺失模式」分層建模並做敏感度分析,用來檢驗主要結論對缺失假設的穩健性。 JAMA Network[41]

JAMA Insights[edit | edit source]

  • Recurrent Clostridioides difficile Infections[42] 中文標題:反覆性困難梭狀桿菌感染 類型:JAMA Insights(臨床要點) 導讀:以臨床實作角度整理復發 CDI 的診斷、治療選項與再發預防重點;若你在住院場景常遇到 CDI,這篇適合當作流程化複習。 JAMA Network[43]

Editor's Note[edit | edit source]

  • AI in the Lab—Will It Really Change Drug Discovery?[44] 中文標題:實驗室中的 AI:真的會改變藥物發現嗎? 類型:Editor's Note 導讀:從研究與產業視角檢視 AI 藥物發現的可行環節與瓶頸(仍需實驗驗證/外部驗證),適合想「校準期待值」的讀者短讀。 JAMA Network[45]
  • “How Strangely Sweet”: Laryngitis and the Quiet Quirkiness of Senryu[46] 中文標題:《多麼奇異的甜美》:喉炎與 Senryu 的靜默怪奇 類型:Editor's Note(醫療人文) 導讀:以喉炎經驗為引,連結 senryu(短詩)與醫學觀察;屬人文短文,適合放鬆閱讀、換換腦袋。 JAMA Network[47]

Medical News[edit | edit source]

  • New Insights on Circadian Health and Cardiometabolic Disease—Light, Sleep, Food, Exercise, and More[48] 中文標題:生理時鐘與心代謝健康:光、睡眠、飲食與運動的新洞見 類型:Medical News 導讀:報導 AHA 科學聲明:把「時間安排」納入處方(光照、睡眠、進食、運動的節律),作為心代謝風險管理的可操作介入方向。 JAMA Network[49]
  • Gluten Sensitivity Is Common Around the World—Explanations Are Emerging[50] 中文標題:全球麩質敏感常見,機轉逐漸明朗 類型:Medical News(Quick Uptakes) 導讀:整理全球非乳糜瀉麩質敏感的盛行與特徵,並討論可能機轉;對消化科/家醫處理「疑似麩質不耐」諮詢有參考價值。 JAMA Network[51]

Medical News in Brief[edit | edit source]

  • 2024-2025 COVID-19 Vaccines Protected Against JN.1 Subvariants[52] 中文標題:2024–2025 COVID-19 疫苗對 JN.1 亞變異株仍具保護 類型:Medical News in Brief 導讀:簡訊整理新一季疫苗對 JN.1 亞變異株的保護訊息,可作為臨床門診與公衛溝通更新的快速素材。 JAMA Network[53]
  • FDA Approves Nonhormonal Treatment for Menopausal Hot Flashes[54] 中文標題:FDA 核准新的非荷爾蒙停經熱潮紅治療 類型:Medical News in Brief 導讀:更新停經熱潮紅的非荷爾蒙治療選項,對不適合或不願使用荷爾蒙療法的族群,臨床可用來做選項式衛教。 JAMA Network[55]
  • [Meta-Analysis: Viral Infections May Raise Cardiovascular Risks](Meta-Analysis: Viral Infections May Raise Cardiovascular Risks) 中文標題:荟萃分析:病毒感染後心血管風險可能上升 類型:Medical News in Brief 導讀:以綜合證據角度提醒病毒感染後可能伴隨心血管風險上升,適合用來提醒高風險病人追蹤與二級預防思維。 JAMA Network[56]
  • Bacterial Vaginosis Treatment Should Involve All Partners, ACOG Says[57] 中文標題:ACOG:細菌性陰道炎治療應納入所有伴侶 類型:Medical News in Brief 導讀:反映對再感染控制的新立場(治療對象擴及所有伴侶);臨床端可先讀這則簡訊,再回頭查實務指引細節。 JAMA Network[58]
  • Updated Flu, RSV Vaccination Recommendations for Immunocompromised People[59] 中文標題:免疫功能低下者流感與 RSV 疫苗建議更新 類型:Medical News in Brief 導讀:快速更新免疫功能低下者的流感/RSV 接種建議,對門診接種排程、衛教與風險溝通有直接應用價值。 JAMA Network[60]
  • [AAP: Leucovorin Not Recommended for Autism](AAP: Leucovorin Not Recommended for Autism) 中文標題:AAP:不建議以 Leucovorin 治療自閉症 類型:Medical News in Brief 導讀:提供門診面對補充/替代療法詢問時的依據與溝通起點;若常遇到家長提及 leucovorin,可先讀此則抓重點。 JAMA Network[61]

Poetry and Medicine[edit | edit source]

  • Hush[62] 中文標題:《安靜》 類型:Poetry and Medicine 導讀:本期詩作短讀,適合在密集研究文章之間換個節奏。 JAMA Network[63]

JAMA Revisited[edit | edit source]

  • Sunshine and Health[64] 中文標題:日照與健康(JAMA Revisited) 類型:JAMA Revisited(歷史回顧) 導讀:重讀歷史內容,回顧「日照與健康」的早期醫學論述;適合教學、人文或醫史興趣讀者。 JAMA Network[65]

JAMA Patient Page[edit | edit source]

  • Early-Onset Gastrointestinal Cancer[66] 中文標題:早發性腸胃道癌症(病人衛教頁) 類型:JAMA Patient Page(Patient Info) 導讀:以病人友善語言整理風險因子、警訊症狀與可能檢查/治療,適合門診衛教、共享決策或做成衛教單張。 JAMA Network[67]

Audio[edit | edit source]

  • Lung Cancer Screening Benefits, Peripheral Neuropathy Review, Arsenic Exposure and Mortality, and more[68] 中文標題:本期音訊總覽:肺癌篩檢、周邊神經病變回顧、砷暴露與死亡等 類型:Audio 導讀:一集把多篇內容串成「可吸收的主線」,適合通勤快聽抓大方向,再回頭挑想深入的研究/評論文章。 JAMA Network[69]
  • The Sequential Organ Failure Assessment (SOFA)-2 Score[70]-2%20Score) 中文標題:SOFA-2 評分:Podcast 導讀 類型:Audio(Podcast) 導讀:聚焦 SOFA-2 的新增構面與臨床使用情境,對 ICU 團隊評估是否導入新評分、如何解讀分數變化很有幫助。 JAMA Network[71]
  • Diagnosis and Management of Cutaneous Melanoma[72] 中文標題:皮膚黑色素瘤的診斷與治療:Podcast 導讀 類型:Audio(Podcast) 導讀:用臨床觀點帶讀黑色素瘤從辨識、診斷到治療路徑,適合皮膚科/腫瘤科/家醫作為快速複習。 edhub.ama-assn.org[73]
  • AI for Drug Discovery[74] 中文標題:AI 用於藥物發現:Podcast 導讀 類型:Audio(Podcast) 導讀:從 drug discovery 流程切入,討論 AI 可用場景與限制;若你關注轉譯研究或新藥研發,這集可快速對齊語境。 JAMA Network[75]

Comment & Response[edit | edit source]

  • Telehealth and Online Cognitive Behavioral Therapy–Based Treatments for High-Impact Chronic Pain[76] 中文標題:遠距/線上 CBT 慢性疼痛治療研究的讀者來函(之一) 類型:Comment & Response 導讀:就「遠距與線上 CBT 治療高衝擊慢性疼痛」研究提出解讀/方法學意見;若你讀過原研究,這封來函可快速看到爭點。 JAMA Network[77]
  • Telehealth and Online Cognitive Behavioral Therapy–Based Treatments for High-Impact Chronic Pain[78] 中文標題:遠距/線上 CBT 慢性疼痛治療研究的讀者來函(之二) 類型:Comment & Response 導讀:另一組作者針對同一主題提出補充觀點;適合想掌握不同讀者如何詮釋同一試驗結果的人快速掃讀。 JAMA Network[79]
  • Telehealth and Online Cognitive Behavioral Therapy–Based Treatments for High-Impact Chronic Pain—Reply[80] 中文標題:作者回覆:遠距/線上 CBT 慢性疼痛治療研究 類型:Comment & Response(Reply) 導讀:原作者回覆並澄清研究設計與結果詮釋,提供「如何讀懂這篇研究」的關鍵線索;建議與來函對照閱讀。 JAMA Network[81]
  • Review on Uveitis[82] 中文標題:葡萄膜炎回顧文的讀者來函 類型:Comment & Response 導讀:針對 uveitis 回顧文章提出補充/質疑與臨床提醒;若你在眼科或內科常遇到 uveitis,這類來函可抓到爭議點。 JAMA Network[83]
  • Review on Uveitis—Reply[84] 中文標題:作者回覆:葡萄膜炎回顧文 類型:Comment & Response(Reply) 導讀:作者回覆並補充其建議的理由與證據來源;適合在讀者來函後,用來釐清回顧文的臨床立場。 JAMA Network[85]
  • Lower Urinary Tract Symptoms in Males[86] 中文標題:男性下泌尿道症狀(LUTS)議題讀者來函(之一) 類型:Comment & Response 導讀:針對男性 LUTS 的評估/治療觀點提出來函意見;可用來快速掃描臨床共識與分歧,之後再回讀原文更有效率。 JAMA Network[87]
  • Lower Urinary Tract Symptoms in Males[88] 中文標題:男性下泌尿道症狀(LUTS)議題讀者來函(之二) 類型:Comment & Response 導讀:另一封針對 LUTS 的補充/不同角度來函;若你在泌尿科/家醫門診常處理 LUTS,建議與其他來函並讀抓重點。 JAMA Network[89]
  • Lower Urinary Tract Symptoms in Males[90] 中文標題:男性下泌尿道症狀(LUTS)議題讀者來函(之三) 類型:Comment & Response 導讀:第三封針對 LUTS 的來函意見,提供不同作者的臨床詮釋;適合用來補齊指引解讀與實務落地的盲點。 JAMA Network[91]
  • Lower Urinary Tract Symptoms in Males—Reply[92] 中文標題:作者回覆:男性 LUTS 議題 類型:Comment & Response(Reply) 導讀:作者整合多封來函的焦點並回覆,適合用來釐清 LUTS 評估與治療路徑的核心邏輯;建議作為總結段閱讀。 JAMA Network[93]

JAMA Masthead[edit | edit source]

  • JAMA[94] 中文標題:JAMA 編輯與委員名錄(Masthead) 類型:JAMA Masthead 導讀:列出期刊編輯、編委與工作人員名錄;臨床讀者可略過,但投稿、引用或查詢期刊運作資訊時很實用。 JAMA Network[95]

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