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Openai/695f02d3-11f8-800e-993a-ad71db6d42aa
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==== In the REGAL trial context (from the November 14, 2022 press release): ==== * An HR of 0.636 means that, at any point in time, patients in the treatment arm (e.g., GPS) had about 36% lower hazard (instantaneous risk) of death than patients in the control arm (e.g., BAT). * This is a relative measure over the entire follow-up period under the proportional hazards assumption (i.e., the ratio is constant over time). Wikipedia<ref>{{cite web|title=Wikipedia|url=https://en.wikipedia.org/wiki/Hazard_ratio|publisher=en.wikipedia.org|access-date=2026-01-10}}</ref> So the trial planners prespecified that an HR β€ 0.636 would be the threshold for demonstrating statistically significant improvement in overall survival (OS).
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