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Openai/6963c099-ff20-8011-adc8-8f1339cd1c1b
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==== π What the Evidence Shows (Human-Level) ==== | Outcome | Evidence strength | Examples | | ---------------------------------------- | ------------------- | ------------------------------------------------------------------------------------------- | | Muscle protein synthesis (MPS) | Limited/conditional | BCAAs activate anabolic signaling, but sustained MPS requires other EAAs. PMC +1 | | Muscle soreness/damage markers | Moderate | Meta-analyses show reduced CK and soreness with BCAA. PMC | | Muscle performance/strength | Weak/inconsistent | Some recent studies in older adults suggest benefit; not robustly consistent overall. MDPI | | Lean mass preservation in weight loss | No clear benefit | 2021 trial showed no lean mass preservation. PubMed | | Fat oxidation/efficiency during exercise | Emerging evidence | 2025 study found increased fat oxidation and reduced fatigue. PubMed |
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