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Openai/69177fbb-14c4-800f-bc57-ccb5a1d88c95
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===== 1. Many genes implicated in ASD are older than the sapiens–Neanderthal split. ===== # Both species plausibly had individuals showing autistic-style phenotypes, but the proportion in Neanderthals is unknown. # Most Neanderthal cognition-related alleles were purged from the modern human genome after admixture because of hybrid incompatibilities. # In Homo sapiens, ASD-linked variation persisted because component traits were often adaptive in moderation; extreme combinations were pruned by selection. # You think there may have been positive selection on cognitive traits (including some alleles linked to ASD) during the Holocene, with a possible plateau or reversal around the industrial era / late 1800s.
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